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博士&硕士生导师
谭保才, 院长
作者:   时间:2017-12-12   点击数:

谭保才, 院长

电 话: 0532-5863-0801, 传 真: 0532-5863-0009, E-Mail: bctan@sdu.edu.cn

教育背景

起止时间 学位 毕业院校 专业学科

1992/09-1997/06 博士 佛罗里达大学(美国) 植物分子遗传学

1984/09-1987/06 硕士 兰州大学 植物生理学

1980/09-1984/06 学士 兰州大学 植物生理学

工作经历

2013/05- 至 今 太阳商城贵宾会2017Cm院长、特聘教授、泰山学者

2011/01-2013/12 香港中文大学深圳研究院 研究员

2007/12-2013/12 香港中文大学植物分子与农业技术研究所 研究副教授

2001/03-2007/12 佛罗里达大学癌症与遗传研究所 研究助理教授

1997/07-2001/02 佛罗里达大学植物分子与细胞生物学 博士后

1992/08-1997/06 佛罗里达大学园艺科学系 研究助理

1987/06-1992/08 兰州大学生物系 讲师

科研方向

1.种子发育的遗传调控机制

种子发育直接影响粮食作物的产量,因此解析种子发育的分子遗传调控机制,既是植物分子遗传学的一个根本问题,也是农业生产高产育种的重要基础。种子发育过程涉及复杂的遗传调控网络,突变体是解析遗传网络组成元件的主要遗传材料。澳门太阳城利用Mutator转座子分离了大量的玉米种子发育突变体,也开发了针对性的快速基因克隆方法,通过对这些突变体的遗传学、分子生物学和细胞生物学分析,克隆调节种子发育的关键基因、查明分子功能、解析其调控种子发育的机制和遗传网络,为分子育种提供理论基础。

2.类胡萝卜素的合成与代谢

维生素A是人类健康必需的营养元素,缺乏维生素A,轻则造成免疫力下降,重则造成夜盲、失明和发育受阻、甚至死亡。遗憾的是人体不能自主合成维生素A,必需靠食物摄取。植物中维生素A原(proVitamin A)是维生素A的前体,可在小肠中转化为维生素A,维生素A原属于类胡萝卜素类物质。因此,本研究旨在研究类胡萝卜素的合成与代谢机制,为高维生素A原的谷物创建奠定基础。

3.ABA合成的调控机制

植物激素ABA在种子休眠和环境应答中起关键作用,胁迫条件下植物可迅速合成ABA,调节一系列基因表达应对环境变化。但从植物感知胁迫到如何启动ABA合成的机制还不清楚。在胁迫条件下,ABA合成的关键基因NCED/Vp14的表达迅速升高。因此,本研究旨在通过对NCED/Vp14的分子生物学研究,探索ABA合成的上游调控基因和通路。

(招收以上各研究方向的硕士、博士研究生和博士后研究人员)

主持课题

1. 2018-2019玉米籽粒大小主要遗传网络的解析和分子机制研究,国家自然科学基金重大研究计划集成项目(主持)。

2. 2017-2021玉米种子发育关键PPR基因的功能和作用机理研究,国家自然科学基金重点项目(主持)。

3. 2015-2017玉米籽粒形成关键基因的克隆和生物学功能分析,国家自然科学基金重大研究计划重点项目(主持)。

4. 2014-2016 Functional analysis of SMALL KERNEL 11 and identification of its interacting proteins, Hong Kong Research Grants Council (主持)。

5. 2013-2015 Functional analysis of Empty pericarp 5 in maize seed development, Hong Kong Research Grants Council (主持)。

6. 2012-2015玉米小籽粒基因Smk2的克隆和功能分析,国家自然科学基金面上项目(主持)。

7. 2012-2014 Functional analysis of EMB15 in maize seed development, Hong Kong Research Grants Council (主持).

8. 2012-2016 Applied research of plant molecular biotechnology on modern agriculture, Shenzhen Peacock Scheme (共同主持)。

9. 2011-2013 Functional analysis of SMK2 in maize, CUHK Shenzhen Research Institute Start-up Support Scheme (主持)。

10. 2010-2012 Genetic and functional dissection of Emb12 and Emb14 in maize embryo development, Hong Kong Research Grants Council (主持).

代表性研究成果

*Corresponding author通讯作者

1. Xu, C., Shen, Y., Li, C., Lu, F., Zhang, M.D., Meeley, R.B., McCarty, D.R. Tan, B.C.* (2021). Emb15 encodes a plastid ribosomal assembly factor essential for embryogenesis in maize. Plant J. DOI: 10.1111/tpj.15160.

2. Yang, Y.Z., Ding, S., Liu, X.Y., Tang, J.J., Wang, Y., Sun, F., Xu, C., Tan, B.C.* (2021). EMP32 is required for the cis-splicing of nad7 intron 2 and seed development in maize. RNA Biology 18: 499-509.

3. Xiu, Z.H.#, Peng, L.#, Wang, Y., Yang, H.H., Sun, F., Wang, X., Cao, S.K., Jaing, R., Wang, L., Chen, B.Y., Tan, B.C.* (2020). Empty Pericarp24 and Empty Pericarp25 are required for the splicing of mitochondrial introns, complex I assembly and seed development in maize. Front. Plant Sci. 11: 608550.

4. Xu, C., Song, S., Yang, Y.Z., Lu, F., Zhang, M.D., Sun, F., Jia, R., Song, R., Tan, B.C.* (2020). DEK46 performs C-to-U editing of a specific site in mitochondrial nad7 introns that is critical for intron splicing and seed development in maize. Plant J. 103: 1767-1782.

5. Liu, R., Cao, S.K., Sayyed, A., Yang, H.H., Zhao J., Wang, X.M., Jia, R.X., Sun, F., Tan, B.C.* (2020). The DYW-subgroup pentatricopeptide repeat protein PPR27 interacts with ZmMORF1 to facilitate mitochondrial RNA editing and seed development in maize. J. Exp. Bot. 71: 5495-5505.

6. Wang, H.C., Chen, Z., Yang, Y.Z., Sun, F., Ding, S., Li, X.L., Xu, C., Tan, B.C.* (2020). PPR14 interacts with a PPR-SMR protein and a CRM protein to mediate the splicing of mitochondrial group II introns in maize. Front. Plant Sci. 11: 814.

7. Liu, R., Cao, S.K., Sayyed, A., Sun, F., Wang, X., Xu, C., Tan, B.C.* (2020). The mitochondrial pentatricopeptide repeat protein PPR18 is required for the cis-splicing of nad4 intron 1 and essential to seed development in maize. Int. J. Mol. Sci. 21: 4047.

8. Yang H., Xiu, Z., Wang, L., Cao, S.K., Li, X., Sun, F., Tan, B.C.* (2020). Two pentatricopeptide repeat proteins are required for the splicing of nad5 introns in maize. Front. Plant Sci. 11: 732.

9. Yang Y.Z., Ding, S., Wang, Y., Wang, H.C., Liu, X.Y., Sun, F., Xu, C., Liu, B., Tan, B.C.* (2020). PPR20 is required for the cis-splicing of mitochondrial nad2 intron 3 and seed development in maize. Plant Cell Physiol. 61: 370–380.

10. Wang, H.C., Sayyed, A., Liu, X.Y., Yang, Y.Z., Sun, F., Wang, Y., Wang, M.D., Tan, B.C.* (2020). SMALL KERNEL4 is required for mitochondrial cox1 transcript editing and seed development in maize. JIPB. 62: 777-792.

11. Wang Y., Liu, X.Y., Yang, Y.Z., Huang, J., Sun, F., Lin, J.S., Gu, Z.Q., Sayyed, A., Xu, C., Tan, B.C.* (2019). Empty pericarp21 encodes a novel PPR-DYW protein that is required for mitochondrial RNA editing at multiple sites, complexes I and V biogenesis, and seed development in maize. PLoS Genetics 15(8): e1008305.

12. Chen, Z.#, Wang, H.C.#, Shen, J., Sun, F., Wang M.D. Xu, C., Tan, B.C.* (2019). PPR-SMR1 is required for the splicing of multiple mitochondrial introns and interacts with Zm-mCSF1 and is essential for seed development in maize. J. Exp. Bot. 70: 5245-5258.

13. Sun, F., Xiu, Z., Jiang, R., Liu, Y., Zhang, X., Yang, Y.Z., Li, X., Zhang, X., Wang, Y., Tan, B.C.* (2019). The mitochondrial pentatricopeptide repeat protein EMP12 is involved in the splicing of three nad2 introns and seed development in maize. J. Exp. Bot. 70: 963-972.

14. Li, X.L., Huang, W.L., Jiang R.C., Sun, F., Wang, H.C., Zhao, J., Xu, C., Tan, B.C.* (2019). EMP18 functions in mitochondrial atp6 and cox2 transcript editing and is essential to seed development in maize. New Phytol. 221: 896-907.

15. Sun, F., Zhang, X., Shen, Y., Wang, H., Liu, R., Wang, X., Gao, D., Yang, Y.Z., Liu, Y., Tan, B.C.* (2018). The pentatricopeptide repeat protein EMPTY PERICARP8 is required for the splicing of three mitochondrial introns and seed development in maize. Plant J. 95: 919-932.

16. Zhang Y.F., Suzuki M., Sun F., Tan B.C.* (2017). The mitochondrion-targeted PENTATRICOPEPTIDE REPEAT78 protein is required for nad5 mature mRNA stability and seed development in maize. Mol. Plant 10: 1321-1333.

17. Yang Y.Z., Ding S., Wang Y., Li C.L., Shen Y., Meeley R., McCarty D.R., Tan B.C.* (2017). Small kernel2 encodes a glutaminase in Vitamin B6biosynthesis and is essential for maize seed development. Plant Physiol. 174: 1127-1138.

18. Cai M., Li S., Sun F., Sun Q., Zhao H., Ren X., Zhao Y., Tan B.C., Zhang Z.*, Qiu F.* (2017). Emp10 encodes a mitochondrial PPR protein that affects the cis-splicing of nad2 intron 1 and seed development in maize. Plant J. 91: 132-144.

19. Tan B.C., Guan J.C., Ding S., Wu S., Koch K.E., McCarty D.R.* (2017). Structure and origin of the White Cap locus and its role in the evolution of grain color in maize. Genetics 206: 135-150. (Commentary by Thomas Peterson (2017). Transposon Storm Kicks off a White Cap. Genetics 206: 87-89.)

20. Yang Y.Z., Ding S., Wang H.C., Sun F., Huang W.L., Song S., Xu C.H., Tan B.C.* (2017). The pentatricopeptide repeat protein EMP9 is required for mitochondrial ccmB and rps4 transcript editing, mitochondrial complex biogenesis and seed development in maize. New Phytol. 214: 782-795.

21. Xiu Z., Sun F., Shen Y., Zhang X., Jiang R., Bonnard G., Zhang J., Tan B.C.* (2016). EMPTY PERICARP16 is required for mitochondrial nad2 intron 4 cis-splicing and seed development in maize. Plant J. 85: 507-519.

22. Li C., Shen Y., Meeley R., McCarty D.R., Tan, B.C.* (2015). Embryo defective 14 encodes a plastid-targeted cGTPase essential for embryogenesis in maize. Plant J. 84: 785-799.

23. Sun F., Wang X., Bonnard G., Shen Y., Xiu Z., Li, X., Gao, D., Zhang, Z., Tan B.C.* (2015). Empty pericarp 7 encodes a mitochondrial E-subgroup pentatricopeptide repeat protein that is required for ccmFN editing, mitochondrial function and seed development in maize. Plant J. 84: 283-295.

24. Chen Y., Tan B.C.* (2015). New insight in the Gibberellin biosynthesis and signal transduction. Plant Signaling & Behavior 10:5, e1000140.

25. Chen Y., Hou M., Liu L., Wu S., Shen Y., Ishiyama K., Kobayashi M., McCarty D.R., Tan B.C.* (2014). The maize DWARF 1 encodes a Gibberellin 3-oxidase and is dual-localized to the nucleus and cytosol. Plant Physiol. 166: 2028-2039.

26. Li X.J., Zhang Y.F., Hou M.M., Sun F., Shen Y., Xiu Z.H., Wang X.M., Chen Z.L., Sun S.S.M., Small I., Tan B.C.* (2014). Small kernel 1 encodes a pentatricopeptide repeat protein required for mitochondrial nad7 transcript editing and seed development in maize and rice. Plant J. 79: 797–809.

27. Yang Y.Z., Tan B.C.* (2014). A distal ABA responsive element in AtNCED3 promoter is required for positive feedback regulation of ABA biosynthesis in Arabidopsis. PLoS One 9: e87283.

28. Zhang Y.F., Hou M.M., Tan B.C.* (2013). The requirement of WHIRLY1 for embryogenesis is dependent on genetic background in maize. PLoS One 8: e67369.

29. Shen Y., Li C., Meeley R., McCarty D.R., Tan B.C.* (2013). Embryo defective 12 encodes translation initiation factor 3 and is essential to maize embryogenesis. Plant J. 74: 792-804.

30. Liu Y., Xiu Z.H., Meeley R., Tan B.C.* (2013). Empty pericarp 5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize. Plant Cell 25: 868-883.

31. Tan B.C.*, Chen Z., Shen Y., Zhang Y., Lai J., Sun S.S.M. (2011). Identification of an active new Mutator transposable element in maize. G3 1: 293-302.

32. Messing S.A., Gabelli S.B., Echeverria I., Vogel J.T., Guan J.C., Tan B.C., Klee H.J., McCarty D.R., Amzel L.M. (2010). Structural insights into maize Viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell 22: 2970-2980.

33. Vogel J.T., Tan B.C., McCarty D.R., Klee H.J. (2008). The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions. J. Biol. Chem. 283: 11364-1137.

34. Settles A.M. Holding D.R., Tan B.C., et al., (2007). Sequence-indexed mutations in maize using the Uniform Mu transposon-tagging population. BMC Genomics 8: 116-124.

35. McCarty D.R., Settles A.M., Suzuki M., Tan B.C., Latshaw S., Porch T., Robin K., Baier J., Avigne W., Lai J., Messing J., Koch K.E., Hannah L.C. (2005) Steady-state transposon mutagenesis in inbred maize. Plant J. 44: 52-61.

36. Tan B.C.*, Joseph L.M., Deng W.T., Liu L.J., Li Q.B., Cline K., McCarty D.R. (2003). Molecular characterization of the Arabidopsis nine-cis-expoxycarotenoid dioxygenase gene family. Plant J. 35: 44-56.

37. Tan B.C.*, Cline K., McCarty D.R. (2001). Localization and targeting of VP14 epoxy-carotenoid dioxygenase to the chloroplast membrane. Plant J. 27: 373-382.

38. Tan B.C., Schwartz S., Zeevaart J.A., McCarty D.R.* (1997). Genetic control of abscisic acid synthesis in maize. Proc. Natl. Acad. Sci. USA 94: 12235-12240.

39. Schwartz S.*, Tan B.C.*, (*Co-first author), Gage D.A., Zeevaart J.A., McCarty D.R.* (1997). Specific oxidative cleavage of carotenoids by VP14 of maize. Science 276: 1872-1875.

奖励

1. Award of Excellence in Graduate Research, University of Florida, 1998 (佛罗里达大学优秀博士毕业论文奖)

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